Bhaskar Chakraborty: Greener Chemistry on the Synthesis and Cycloaddition Reactions

Greener Chemistry on the Synthesis and Cycloaddition Reactions


Description

The utility of nitrones in synthetic organic chemistry has been widely illustrated. The nitrone moiety can be regarded as a 3 centered dipolar 4 system, which enables 1,3-dipolar cycloaddition reactions with different dipolarophilic reagent to occur. 1,3-dipolar cycloaddition reaction between a nitrone and an olefinic dipolarophiles is an efficient method for the synthesis of isoxazolidine and isoxazoline ring systems. Nitrones are also versatile intermediates for the synthesis of natural products and many biologically interesting molecules. Owing to the labile nature of the N-O bond under mild reducing conditions, isoxazolidines provide easy access to a variety of fascinating 1,3-difunctional amino alcohols. To run a chemical reaction under an environment friendly condition is a challenge now-adays. The development of environmentally benign chemical processes (aqueous phase synthesis, microwave induced reactions and ionic liquids as solvent) have received much attention in recent years.

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Author: Bhaskar Chakraborty
Number of Pages: 92 pages
Published Date: 29 Sep 2011
Publisher: LAP Lambert Academic Publishing
Publication Country: Germany
Language: English
ISBN: 9783845429267
Download Link: Click Here
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